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Serena Williams will try to move one step closer toward Grand Slam No. 22 on Wednesday night when she faces the fourth-seeded Agnieszka Radwanska in an Australian Open women's semifinal.

Williams appears back on top of her game after a disappointing end to the 2015 season at the U.S. Open. The 21-time major champion has yet to lose a set at this year's Australian Open, and she is coming off a dominant win over fifth-seeded Maria Sharapova (6-4, 6-1). Radwanska is the clear underdog, but she enters the semifinal fresh off a 6-1, 6-3 win over 10th-seeded Carla Suarez Navarro.

Will Williams' hopes for a seventh Australian Open championship remain alive, or will Radwanska shock the tennis world? You can watch it all unfold online here:

When: Wednesday, Jan. 27, 9:30 p.m. ET
Watch: Watch ESPN

Thumbnail photo via Twitter/@SInow