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5:45 p.m. ET: The New England Patriots face their toughest test to date Sunday night, traveling to take on the Denver Broncos.

The Patriots could have handily beat the Broncos if not for a wave of injuries that has depleted their receiver, linebacker, offensive line and defensive back corps.

With Danny Amendola and Julian Edelman out, Brandon LaFell, Chris Harper and Keshawn Martin must step up. With Jamie Collins out with an illness, Jonathan Freeny, Jerod Mayo and Jon Bostic will have to emerge.

Nate Solder was placed on injured reserve early in the season, which has forced Marcus Cannon to take over a starting role. Cornerback Justin Coleman was ruled out Friday with a hand injury, and safety Patrick Chung was a late addition to the injury report Sunday with a foot ailment. We'll see if he can go at 7 p.m. ET, when the inactives are released. If he can't, Duron Harmon, Jordan Richards and Tavon Wilson will have to take on multiple roles at cornerback and safety.

Stay here for updates and analysis throughout the game.

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Thumbnail photo via Chris Humphreys/USA TODAY Sports Images